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 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">Tavricheskiy Mediko-Biologicheskiy Vestnik</journal-id>
   <journal-title-group>
    <journal-title xml:lang="en">Tavricheskiy Mediko-Biologicheskiy Vestnik</journal-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Таврический медико-биологический вестник</trans-title>
    </trans-title-group>
   </journal-title-group>
   <issn publication-format="print">2070-8092</issn>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="publisher-id">109213</article-id>
   <article-id pub-id-type="doi">10.29039/2070-8092-2025-28-1-51-56</article-id>
   <article-categories>
    <subj-group subj-group-type="toc-heading" xml:lang="ru">
     <subject>Клинический случай</subject>
    </subj-group>
    <subj-group subj-group-type="toc-heading" xml:lang="en">
     <subject>Clinical observations</subject>
    </subj-group>
    <subj-group>
     <subject>Клинический случай</subject>
    </subj-group>
   </article-categories>
   <title-group>
    <article-title xml:lang="en">CARE OF AN EXTENSIVE LONG-TERM NON-HEALING WOUND OF THE ANKLE  JOINT AND FOOT WITHOUT SYSTEMIC ANTIBIOTICS</article-title>
    <trans-title-group xml:lang="ru">
     <trans-title>ЛЕЧЕНИЕ ОБШИРНОЙ ДЛИТЕЛЬНО НЕЗАЖИВАЮЩЕЙ РАНЫ  ГОЛЕНОСТОПНОГО СУСТАВА И СТОПЫ БЕЗ ПРИМЕНЕНИЯ  СИСТЕМНЫХ АНТИБАКТЕРИАЛЬНЫХ ПРЕПАРАТОВ</trans-title>
    </trans-title-group>
   </title-group>
   <contrib-group content-type="authors">
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Саркисян</surname>
       <given-names>О. Г.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Sarkisyan</surname>
       <given-names>O. G.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Сурков</surname>
       <given-names>А. Н.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Surkov</surname>
       <given-names>A. N.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-2"/>
     <xref ref-type="aff" rid="aff-3"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Бабич</surname>
       <given-names>И. И.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Babich</surname>
       <given-names>I. I.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-1"/>
     <xref ref-type="aff" rid="aff-4"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Пархомина</surname>
       <given-names>Н. А.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Parhomina</surname>
       <given-names>N. A.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-5"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Захарьян</surname>
       <given-names>Е. А.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Zahar'yan</surname>
       <given-names>E. A.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-6"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Лосева</surname>
       <given-names>Т. Д.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Loseva</surname>
       <given-names>T. D.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Черепанова</surname>
       <given-names>А. А.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Cherepanova</surname>
       <given-names>A. A.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-7"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Батыщева</surname>
       <given-names>О. Е.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Batyscheva</surname>
       <given-names>O. E.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-8"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Вавилова</surname>
       <given-names>Н. С.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Vavilova</surname>
       <given-names>N. S.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-9"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Гончаров</surname>
       <given-names>Е. Ю.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Goncharov</surname>
       <given-names>E. Yu.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-10"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Лозовая</surname>
       <given-names>П. К.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Lozovaya</surname>
       <given-names>P. K.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-11"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Гумер</surname>
       <given-names>Р. Б.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Gumer</surname>
       <given-names>R. B.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-12"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Сергиенко</surname>
       <given-names>Т. О.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Sergienko</surname>
       <given-names>T. O.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-13"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Гончарук</surname>
       <given-names>Л. Н.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Goncharuk</surname>
       <given-names>L. N.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-14"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Щербакова</surname>
       <given-names>И. Ю.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Scherbakova</surname>
       <given-names>I. Yu.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-15"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Фокин</surname>
       <given-names>Е. В.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Fokin</surname>
       <given-names>E. V.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-16"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Попов</surname>
       <given-names>И. В.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Popov</surname>
       <given-names>I. V.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-17"/>
    </contrib>
   </contrib-group>
   <aff-alternatives id="aff-1">
    <aff>
     <institution xml:lang="ru">Ростовский государственный медицинский университет</institution>
    </aff>
    <aff>
     <institution xml:lang="en">Rostov State Medical University</institution>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-2">
    <aff>
     <institution xml:lang="ru">Российский национальный исследовательский медицинский университет им. Н.И. Пирогова</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Российский национальный исследовательский медицинский университет им. Н.И. Пирогова</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-3">
    <aff>
     <institution xml:lang="ru">Российский научный центр хирургии им. акад Б. В. Петровского</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Российский научный центр хирургии им. акад Б. В. Петровского</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-4">
    <aff>
     <institution xml:lang="ru">Областная детская клиническая больница</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Областная детская клиническая больница</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-5">
    <aff>
     <institution xml:lang="ru">Детская городская больница</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Детская городская больница</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-6">
    <aff>
     <institution xml:lang="ru">Национальный медицинский исследовательский центр детской травматологии и ортопедии имени Г. И. Турнера</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Национальный медицинский исследовательский центр детской травматологии и ортопедии имени Г. И. Турнера</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-7">
    <aff>
     <institution xml:lang="ru">Детская городская больница</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Детская городская больница</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-8">
    <aff>
     <institution xml:lang="ru">Детская городская больница</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Детская городская больница</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-9">
    <aff>
     <institution xml:lang="ru">Детская городская больница</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Детская городская больница</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-10">
    <aff>
     <institution xml:lang="ru">Детская городская больница</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Детская городская больница</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-11">
    <aff>
     <institution xml:lang="ru">Детская городская больница</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Детская городская больница</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-12">
    <aff>
     <institution xml:lang="ru">Детская городская больница</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Детская городская больница</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-13">
    <aff>
     <institution xml:lang="ru">Детская городская больница</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Детская городская больница</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-14">
    <aff>
     <institution xml:lang="ru">Центральная городская больница</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Центральная городская больница</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-15">
    <aff>
     <institution xml:lang="ru">Центральная городская больница</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Центральная городская больница</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-16">
    <aff>
     <institution xml:lang="ru">Детская городская больница</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Детская городская больница</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-17">
    <aff>
     <institution xml:lang="ru">Областная детская клиническая больница</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Областная детская клиническая больница</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <pub-date publication-format="print" date-type="pub" iso-8601-date="2025-12-03T11:24:41+03:00">
    <day>03</day>
    <month>12</month>
    <year>2025</year>
   </pub-date>
   <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2025-12-03T11:24:41+03:00">
    <day>03</day>
    <month>12</month>
    <year>2025</year>
   </pub-date>
   <volume>28</volume>
   <issue>1</issue>
   <fpage>51</fpage>
   <lpage>56</lpage>
   <history>
    <date date-type="received" iso-8601-date="2025-12-02T00:00:00+03:00">
     <day>02</day>
     <month>12</month>
     <year>2025</year>
    </date>
   </history>
   <self-uri xlink:href="https://ma.cfuv.ru/wp-content/uploads/2025/11/7_&#x421;&#x410;&#x420;&#x41A;&#x418;&#x421;&#x42F;&#x41D;.doc">https://ma.cfuv.ru/wp-content/uploads/2025/11/7_САРКИСЯН.doc</self-uri>
   <abstract xml:lang="ru">
    <p>Гнойная патология составляет более 70% в структуре хирургических заболеваний. При этом &#13;
значительную ее долю составляют гнойно-воспалительные процессы мягких тканей, а наиболее часто &#13;
рекомендуемым способом лечения является антибактериальная терапия. Однако, в настоящее время, &#13;
перед врачом первичного звена здравоохранения стоит задача поиска способов лечения с минимальным &#13;
применением антибиотиков в связи с развитием антибиотикорезистентных штаммов и значительного &#13;
количества осложнений. В статье представлены результаты лечения пациента 15 лет с обширной &#13;
ушибленной раной голеностопного сустава и стопы, лечение которой успешно проведено с помощью &#13;
местного применения спиртового раствора 0,027% хлоргексидина биглюконата без использования &#13;
системных антибактериальных препаратов. Пациенту проводили обработку раны с удалением старых &#13;
марлевых повязок промыванием 3% раствором перекиси водорода, затем рана закрывалась марлевой &#13;
салфеткой, смоченной 0,027% спиртовым раствором хлоргексидина биглюконата, а также фиксирующим &#13;
марлевым бинтом. В течение суток процедура повторялась 6-8 раз. Процентное соотношение компонентов &#13;
используемого раствора составила: хлоргексидин 0,05% – 50%, спирт этиловый ректификованный 95%  – &#13;
21,1%, вода дистиллированная – 28,9%. Пациенту удалось купировать воспалительный процесс мягких &#13;
тканей голеностопного сустава и стопы с применением слабо концентрированного спиртового раствора &#13;
хлоргексидина биглюконата, а также отказаться от применения системных антибактериальных препаратов. &#13;
При этом не отмечалось химического ожога и дубления кожных покровов и мягких тканей области раны,  процедура легко переносилась пациентом, не вызывала болезненных ощущений, в связи с чем может &#13;
быть рекомендована к применению.</p>
   </abstract>
   <trans-abstract xml:lang="en">
    <p>Purulent pathology accounts for more than 70% of the structure of surgical diseases, while purulent&#13;
inflammatory processes of soft tissues make up a significant proportion of it, and the most often recommended &#13;
treatment method is antibacterial therapy. However, currently the primary care physician is faced with the task of &#13;
f&#13;
 inding ways to treat with minimal use of antibiotics due to the development of antibiotic-resistant strains and a &#13;
significant number of complications. The article presents the results of treatment of a 15-year-old patient with an &#13;
extensive bruised ankle and foot wound. Patient was successfully treated with topical application of an alcohol &#13;
solution of 0.027% chlorhexidine bigluconate without the use of systemic antibacterial drugs. The patient was &#13;
treated with the removal of old gauze bandages, rinsing with a 3% solution of hydrogen peroxide, then the wound &#13;
was closed with a gauze cloth moistened with 0.027% alcohol solution of chlorhexidine bigluconate, as well as a &#13;
f&#13;
 ixing gauze bandage. The procedure was repeated 6-8 times during the day. The percentage of components of &#13;
the solution used was: chlorhexidine 0.05% – 50%, rectified ethyl alcohol 95% – 21.1%, distilled water – 28.9%. &#13;
The patient managed to stop the inflammatory process of the soft tissues of the ankle joint and foot with the &#13;
use of a weakly concentrated alcoholic solution of chlorhexidine bigluconate, as well as to abandon the use of &#13;
systemic antibacterial drugs. At the same time, there was no chemical burn and tanning of the skin and soft &#13;
tissues of the wound area, the procedure was easily tolerated by the patient, did not cause painful sensations, &#13;
and therefore can be recommended for use.</p>
   </trans-abstract>
   <kwd-group xml:lang="ru">
    <kwd>ушибленные раны</kwd>
    <kwd>раствор хлоргексидина биглюконата</kwd>
    <kwd>антибактериальная терапия</kwd>
    <kwd>антибиотикорезистентность</kwd>
    <kwd>воспаление</kwd>
    <kwd>синегнойная  палочка</kwd>
   </kwd-group>
   <kwd-group xml:lang="en">
    <kwd>contused wounds</kwd>
    <kwd>chlorhexidine bigluconate solution</kwd>
    <kwd>antibacterial therapy</kwd>
    <kwd>antibiotic resistance</kwd>
    <kwd>inflammation</kwd>
    <kwd>Pseudomonas aeruginosa</kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
  <p></p>
 </body>
 <back>
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