Scientific Notes of V.I. Vernadsky Crimean Federal University. Biology. Chemistry Scientific Notes of V.I. Vernadsky Crimean Federal University. Biology. Chemistry Ученые записки Крымского федерального университета имени В.И. Вернадского. Биология. Химия. 2413-1725 91775 10.29039/2413-1725-2024-10-3-32-44 БИОЛОГИЧЕСКИЕ НАУКИ BIOLOGICAL SCIENCES БИОЛОГИЧЕСКИЕ НАУКИ FEATURES OF CEREBRAL HEMODYNAMICS IN PEOPLE OF PRE-RETIREMENT AGE ОСОБЕННОСТИ ЦЕРЕБРАЛЬНОЙ ГЕМОДИНАМИКИ У ЛЮДЕЙ ПРЕДПЕНСИОННОГО ВОЗРАСТА Веселовская Е. Д. Veselovskaya E. D. Севрюкова Г. А. Sevryukova G. A. Волгоградский государственный медицинский университет The Volgograd State Medical University 12 12 2024 12 12 2024 10 3 32 44 10 12 2024 https://sn-biolchem.cfuv.ru/osobennosti-czerebralnoj-gemodinamiki-u-lyudej-predpensionnogo-vozrasta/

Статья посвящена исследованию церебральной гемодинамики у людей предпенсионного возраста (женщины n = 104, мужчины n = 83). Эукинетический тип кровообращения отмечался у 52,6 % женщин зрелого возраста второго периода. Преобладание гипокинетического типа у мужчин и женщин пожилого возраста, обусловливает значимые изменения в соотношении церебрального притока крови ее оттоку и свидетельствует о снижении приспособительных реакций системы кровообращения. Люди предпенсионного возраста с гиперкинетическим типом составляют группу риска и имеют значимые отклонения параметров реоэнцефалографии от возрастной нормы. Лимит вазоконстрикторных реакций, обусловленный инволюционными процессами, является причиной ухудшения условий регионарного оттока крови, что необходимо учитывать при проведении функциональных проб у людей старше 50 лет.

The article is devoted to the study of cerebral hemodynamics in people of pre-retirement age, differentiated by age and sex criteria and types of systemic circulation (women (n = 104), men (n = 83). Objective: to research of the features of cerebral hemodynamics in people of pre-retirement age. Evaluation of blood supply to the brain was carried out at rest using the reoencephalographic method. The reoencephalographic examination was performed in 4 leads (FM, OM left hemisphere; FM, OM right hemisphere). Indicators were registered: integral index of pulse filling, amplitude-frequency index, rheographic index and time of propagation of the rheographic wave, average vessel filling rate, venous outflow, dicrotic index, diastolic index and coefficient of asymmetry. The type of systemic circulation was determined using the cardiac index. The predominance of the hypokinetic type in elderly men and women causes significant changes in the ratio of cerebral blood flow to its outflow and indicates a decrease in adaptive reactions of the circulatory system. Many men and older women have a hypo-kinetic circulating type, which may be an unfavorable feature. People of pre-retirement age with hyperkinetic type of blood circulation can be classified as a risk group, because they have significant deviations of rheoencephalography parameters from the physiological norm. Changes in the ratio of regional blood inflow to outflow in people over 50 years of age are markers of a decrease in adaptive reactions of the circulatory system. The limit of vasoconstrictor reactions caused by the aging of the body is the cause of deterioration of the conditions of regional blood outflow. The revealed deviations of rheoencephalography parameters from the physiological norm should be taken into account when conducting functional tests, as well as in programs of prenosological diagnostics, organization of healing and preventive measures.

 реоэнцефалография предпенсионный возраст церебральная гемодинамика тип системного кровообращения. reoencephalography pre-retirement age cerebral hemodynamics type of systemic circulation.

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