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 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">Scientific Notes of V.I. Vernadsky Crimean Federal University. Biology. Chemistry</journal-id>
   <journal-title-group>
    <journal-title xml:lang="en">Scientific Notes of V.I. Vernadsky Crimean Federal University. Biology. Chemistry</journal-title>
    <trans-title-group xml:lang="ru">
     <trans-title>Ученые записки Крымского федерального университета имени В.И. Вернадского. Биология. Химия.</trans-title>
    </trans-title-group>
   </journal-title-group>
   <issn publication-format="print">2413-1725</issn>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="publisher-id">91780</article-id>
   <article-id pub-id-type="doi">10.29039/2413-1725-2024-10-3-79-91</article-id>
   <article-categories>
    <subj-group subj-group-type="toc-heading" xml:lang="ru">
     <subject>БИОЛОГИЧЕСКИЕ НАУКИ</subject>
    </subj-group>
    <subj-group subj-group-type="toc-heading" xml:lang="en">
     <subject>BIOLOGICAL SCIENCES</subject>
    </subj-group>
    <subj-group>
     <subject>БИОЛОГИЧЕСКИЕ НАУКИ</subject>
    </subj-group>
   </article-categories>
   <title-group>
    <article-title xml:lang="en">PROSPECTS OF USING THE BILAR APIPRODUCT TO ENHANCE THE FUNCTIONALITY OF THE ATHLETES’ MICROHEMOCIRCULATION SYSTEM</article-title>
    <trans-title-group xml:lang="ru">
     <trans-title>ПЕРСПЕКТИВЫ ИСПОЛЬЗОВАНИЯ АПИПРОДУКТА «БИЛАР» ДЛЯ ПОВЫШЕНИЯ ФУНКЦИОНАЛЬНЫХ ВОЗМОЖНОСТЕЙ СИСТЕМЫ МИКРОГЕМОЦИРКУЛЯЦИИ СПОРТСМЕНОВ</trans-title>
    </trans-title-group>
   </title-group>
   <contrib-group content-type="authors">
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Кротова</surname>
       <given-names>К. А.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Krotova</surname>
       <given-names>K. A.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-1"/>
    </contrib>
    <contrib contrib-type="author">
     <name-alternatives>
      <name xml:lang="ru">
       <surname>Литвин</surname>
       <given-names>Ф. Б.</given-names>
      </name>
      <name xml:lang="en">
       <surname>Litvin</surname>
       <given-names>F. B.</given-names>
      </name>
     </name-alternatives>
     <xref ref-type="aff" rid="aff-2"/>
    </contrib>
   </contrib-group>
   <aff-alternatives id="aff-1">
    <aff>
     <institution xml:lang="ru">Смоленский государственный университет спорта</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Смоленский государственный университет спорта</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <aff-alternatives id="aff-2">
    <aff>
     <institution xml:lang="ru">Смоленский государственный университет спорта</institution>
     <country>Россия</country>
    </aff>
    <aff>
     <institution xml:lang="en">Смоленский государственный университет спорта</institution>
     <country>Russian Federation</country>
    </aff>
   </aff-alternatives>
   <pub-date publication-format="print" date-type="pub" iso-8601-date="2024-12-12T13:33:56+03:00">
    <day>12</day>
    <month>12</month>
    <year>2024</year>
   </pub-date>
   <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2024-12-12T13:33:56+03:00">
    <day>12</day>
    <month>12</month>
    <year>2024</year>
   </pub-date>
   <volume>10</volume>
   <issue>3</issue>
   <fpage>79</fpage>
   <lpage>91</lpage>
   <history>
    <date date-type="received" iso-8601-date="2024-12-10T00:00:00+03:00">
     <day>10</day>
     <month>12</month>
     <year>2024</year>
    </date>
   </history>
   <self-uri xlink:href="https://sn-biolchem.cfuv.ru/perspektivy-ispolzovaniya-apiprodukta-bilar-dlya-povysheniya-funkczionalnyh-vozmozhnostej-sistemy-mikrogemoczirkulyaczii-sportsmenov/">https://sn-biolchem.cfuv.ru/perspektivy-ispolzovaniya-apiprodukta-bilar-dlya-povysheniya-funkczionalnyh-vozmozhnostej-sistemy-mikrogemoczirkulyaczii-sportsmenov/</self-uri>
   <abstract xml:lang="ru">
    <p>Целью настоящего исследования явилась оценка влияния продукта из трутневых личинок медоносной пчелы  «Билара»  на  стационарные  и  колебательные  характеристики  системы  микроциркуляции спортсменов.  Методом  лазерной  допплеровской  флоуметрии  (ЛДФ)  обследовано  50  спортсменов баскетболистов.  Включение  биопродукта  «Билар»  в  пищевой  рацион  спортсменов  на  этапе предсоревновательного тренировочного цикла оказывает двоякий эффект. В состоянии относительного покоя биопродукт способствует экономизации в работе системы микроциркуляции. При дозированной аэробной нагрузке обеспечивает расширение адаптационных возможностей, через усиление перфузии, нутритивного кровотока и оптимизацию механизмов регуляции и повышение клеточного дыхания.</p>
   </abstract>
   <trans-abstract xml:lang="en">
    <p>The purpose of this study was to evaluate the effect of the product from the drone larvae of the honey bee «Bilara» on the stationary and oscillatory characteristics of the microcirculation system of athletes. 50 athletes of basketball players of the control and main groups were examined by laser Doppler flowmetry (LDF) and fluorescence spectroscopy (FS). The inclusion of the bioprodukt «Bilar» in the diet of athletes at the stage of the pre-competitive training cycle has a twofold effect. After applying Bilar, the nutritional blood flow increases in a state of relative rest, the direct regulator of which is vasodilation of precapillary sphincters. A decrease in the peripheral resistance of precapillary sphincters «facilitates» blood flow into the microvascular bed with the participation of extravascular pulse and respiratory regulation mechanisms. At rest, after «Bilar», the level of oxidative metabolism decreases. In conditions of working hypoxia, activation of vasomotion and flaxmotion increases blood perfusion and the amount of nutritive blood flow. The increase in the intensity of microcirculation is based on a decrease in microvascular tone, which reflects an increase in the amplitude of intravascular mechanisms. Monitoring of fluorescence of NADH and FAD coenzymes in the form of a redox potential showed a significant increase in oxidative metabolism after dosed physical activity.&#13;
The analyzed data indicate the high relevance of the further introduction of drone brood preparations into the nutritional component of the athletes’ diet, which will serve as a tool for improving the physical performance of athletes and accelerated recovery.</p>
   </trans-abstract>
   <kwd-group xml:lang="ru">
    <kwd>лазерная  допплеровская  флоуметрия</kwd>
    <kwd>микроциркуляция</kwd>
    <kwd>спортсмены</kwd>
    <kwd>биопродукт</kwd>
    <kwd>физическая нагрузка</kwd>
    <kwd>колебания кровотока</kwd>
    <kwd>транспорт кислорода</kwd>
   </kwd-group>
   <kwd-group xml:lang="en">
    <kwd>laser Doppler flowmetry</kwd>
    <kwd>microcirculation</kwd>
    <kwd>athletes</kwd>
    <kwd>bioproduct</kwd>
    <kwd>physical activity</kwd>
    <kwd>fluctuations in blood flow</kwd>
    <kwd>oxygen transport.</kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
  <p></p>
 </body>
 <back>
  <ref-list>
   <ref id="B1">
    <label>1.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Garganeeva N. P. [and others], The influence of physical activity of different directions on indicators of physical performance and the level of maximum oxygen consumption in qualified athletes, depending on</mixed-citation>
     <mixed-citation xml:lang="en">Garganeeva N. P. [and others], The influence of physical activity of different directions on indicators of physical performance and the level of maximum oxygen consumption in qualified athletes, depending on</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B2">
    <label>2.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Macdermid P. W., Stannard S. R. A whey-supplemented, high-protein diet versus a high-carbohydrate diet:  effects  on  endurance  cycling  performance,  International  Journal  of  Sport  Nutrition  and  Exercise</mixed-citation>
     <mixed-citation xml:lang="en">Macdermid P. W., Stannard S. R. A whey-supplemented, high-protein diet versus a high-carbohydrate diet:  effects  on  endurance  cycling  performance,  International  Journal  of  Sport  Nutrition  and  Exercise</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B3">
    <label>3.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Borisova  O.  O.  Nutrition  for  athletes:  foreign  experience  and  practical  recommendations  [Text]: educational method. Allowance, 132 (Soviet sport, Moscow, 2007).</mixed-citation>
     <mixed-citation xml:lang="en">Borisova  O.  O.  Nutrition  for  athletes:  foreign  experience  and  practical  recommendations  [Text]: educational method. Allowance, 132 (Soviet sport, Moscow, 2007).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B4">
    <label>4.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Kulinenkov  O.  S.  Pharmacological  assistance  to  an  athlete:  correction  of  factors  limiting  sports performance, 144 (Soviet sport, Moscow, 2007).</mixed-citation>
     <mixed-citation xml:lang="en">Kulinenkov  O.  S.  Pharmacological  assistance  to  an  athlete:  correction  of  factors  limiting  sports performance, 144 (Soviet sport, Moscow, 2007).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B5">
    <label>5.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Kim  V.  N.,  Krivulina  G.  B.,  Shevelev  V.  M.,  Karpov  R.  S.,  Correction  of  endothelium-dependent microcirculation disorders, biochemical blood parameters, level of performance, vegetative and psycho-</mixed-citation>
     <mixed-citation xml:lang="en">Kim  V.  N.,  Krivulina  G.  B.,  Shevelev  V.  M.,  Karpov  R.  S.,  Correction  of  endothelium-dependent microcirculation disorders, biochemical blood parameters, level of performance, vegetative and psycho-</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B6">
    <label>6.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Brook T. M., Litvin F. B. Assessment of the reactivity of the microcirculation system to physical activity with the combined use of natural dietary supplements and LILI in athletes with different types of heart rate</mixed-citation>
     <mixed-citation xml:lang="en">Brook T. M., Litvin F. B. Assessment of the reactivity of the microcirculation system to physical activity with the combined use of natural dietary supplements and LILI in athletes with different types of heart rate</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B7">
    <label>7.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Novikov  V.  S.,  Karkishchenko  V.  N.,  Shustov  E.  B.  Functional  human  nutrition  under  extreme influences, 346 (Politekhnika-print, St. Petersburg, 2017).</mixed-citation>
     <mixed-citation xml:lang="en">Novikov  V.  S.,  Karkishchenko  V.  N.,  Shustov  E.  B.  Functional  human  nutrition  under  extreme influences, 346 (Politekhnika-print, St. Petersburg, 2017).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B8">
    <label>8.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Hinton P. S. Iron and the endurance athlete. Applied Physiology, Nutrition, and Metabolism, 39, 9, 1012 (2014).</mixed-citation>
     <mixed-citation xml:lang="en">Hinton P. S. Iron and the endurance athlete. Applied Physiology, Nutrition, and Metabolism, 39, 9, 1012 (2014).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B9">
    <label>9.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Maughan  R.  J.,  Depiesse  F.,  Geyer  H.  International  Association  of  Athletics  Federations.  The  use  of dietary supplements by athletes, J Sports Sci, 25, 1 (2007).</mixed-citation>
     <mixed-citation xml:lang="en">Maughan  R.  J.,  Depiesse  F.,  Geyer  H.  International  Association  of  Athletics  Federations.  The  use  of dietary supplements by athletes, J Sports Sci, 25, 1 (2007).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B10">
    <label>10.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Potgieter S. Sport nutrition: A review of the latest guidelines for exercise and sport nutrition from the American College of Sport Nutrition, the International Olympic Committee and the International Society</mixed-citation>
     <mixed-citation xml:lang="en">Potgieter S. Sport nutrition: A review of the latest guidelines for exercise and sport nutrition from the American College of Sport Nutrition, the International Olympic Committee and the International Society</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B11">
    <label>11.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Gavrilova E. A. Sports nutrition is an integral component of sports training, 48 (Moscow, 2021).</mixed-citation>
     <mixed-citation xml:lang="en">Gavrilova E. A. Sports nutrition is an integral component of sports training, 48 (Moscow, 2021).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B12">
    <label>12.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Prohoda  I.  A.  New  technology  for  the  production  of  bilar  products.  Beekeeping  –  XXI  century. Beekeeping,  apitherapy  and  quality  of  life:  materials  International.  conf.  (Pishchepromizdat,  Moscow,</mixed-citation>
     <mixed-citation xml:lang="en">Prohoda  I.  A.  New  technology  for  the  production  of  bilar  products.  Beekeeping  –  XXI  century. Beekeeping,  apitherapy  and  quality  of  life:  materials  International.  conf.  (Pishchepromizdat,  Moscow,</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B13">
    <label>13.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Litvin F. B. Prohoda I. A., Morozova E. P., Martynov S. V., The influence of the drug “Bilar” on the autonomic regulation of heart rate in young athletes. Yearbook of the Research Institute of Fundamental and</mixed-citation>
     <mixed-citation xml:lang="en">Litvin F. B. Prohoda I. A., Morozova E. P., Martynov S. V., The influence of the drug “Bilar” on the autonomic regulation of heart rate in young athletes. Yearbook of the Research Institute of Fundamental and</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B14">
    <label>14.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Mitrofanov D. V., Budnikova N. V., Brandorf A. Z. Application of drone brood in rational nutrition and apitherapy, Agricultural science of the Euro-North-East., 22, 2, 188 (2021).</mixed-citation>
     <mixed-citation xml:lang="en">Mitrofanov D. V., Budnikova N. V., Brandorf A. Z. Application of drone brood in rational nutrition and apitherapy, Agricultural science of the Euro-North-East., 22, 2, 188 (2021).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B15">
    <label>15.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Baboshina  N.  V.  Age-related  features  of  the  formation  of  the  microcirculation  system,  its  regulatory mechanisms  and  reserve  capabilities  during  the  periods  of  primary  school,  adolescence  and</mixed-citation>
     <mixed-citation xml:lang="en">Baboshina  N.  V.  Age-related  features  of  the  formation  of  the  microcirculation  system,  its  regulatory mechanisms  and  reserve  capabilities  during  the  periods  of  primary  school,  adolescence  and</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B16">
    <label>16.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Mikhailov P. A., Muravyov A. V., Osetrov I. A., Tikhomirova I. A. Structure of relationships between indicators  of  aerobic  performance  of  central  hemodynamics,  microcirculation  and  blood  rheology,</mixed-citation>
     <mixed-citation xml:lang="en">Mikhailov P. A., Muravyov A. V., Osetrov I. A., Tikhomirova I. A. Structure of relationships between indicators  of  aerobic  performance  of  central  hemodynamics,  microcirculation  and  blood  rheology,</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B17">
    <label>17.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Litvin F. B.. Brook T. M., Terekhov P. A., Prohoda I. A. The influence of a dietary supplement based on drone larvae homogenate on microcirculation and metabolism in cross-country skiers, Sports medicine:</mixed-citation>
     <mixed-citation xml:lang="en">Litvin F. B.. Brook T. M., Terekhov P. A., Prohoda I. A. The influence of a dietary supplement based on drone larvae homogenate on microcirculation and metabolism in cross-country skiers, Sports medicine:</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B18">
    <label>18.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Dunaev A. V. Method and device for assessing the functional state of microcirculatory tissue systems of the  human  body  based  on  multiparametric  optical  diagnostics,  Izv.  universities  in  Russia.</mixed-citation>
     <mixed-citation xml:lang="en">Dunaev A. V. Method and device for assessing the functional state of microcirculatory tissue systems of the  human  body  based  on  multiparametric  optical  diagnostics,  Izv.  universities  in  Russia.</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B19">
    <label>19.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Bykov A. T., Litvin F. B., Baranov V. V., Zhigalo V. Ya., Zezyulya V. S. Assessment of the influence of fermented  whey  on  the  morphofunctional  status  and  performance  of  athletes  during  intense  physical</mixed-citation>
     <mixed-citation xml:lang="en">Bykov A. T., Litvin F. B., Baranov V. V., Zhigalo V. Ya., Zezyulya V. S. Assessment of the influence of fermented  whey  on  the  morphofunctional  status  and  performance  of  athletes  during  intense  physical</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B20">
    <label>20.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Krupatkin A. I., Sidorov V. V., Dunaev A. V., Rafailov E. V. Synchronization of myogenic oscillations of microblood  flow  and  changes  in  oxygen  saturation  –  a  manifestation  of  physiological  adaptation  in</mixed-citation>
     <mixed-citation xml:lang="en">Krupatkin A. I., Sidorov V. V., Dunaev A. V., Rafailov E. V. Synchronization of myogenic oscillations of microblood  flow  and  changes  in  oxygen  saturation  –  a  manifestation  of  physiological  adaptation  in</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B21">
    <label>21.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Krupatkin  A.  I.,  Sidorov  V.  V.  The  problem  of  adaptation  and  oscillatory  processes  in  the microcirculatory bed, Human Physiology, 42, 4, 69 (2016).</mixed-citation>
     <mixed-citation xml:lang="en">Krupatkin  A.  I.,  Sidorov  V.  V.  The  problem  of  adaptation  and  oscillatory  processes  in  the microcirculatory bed, Human Physiology, 42, 4, 69 (2016).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B22">
    <label>22.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Dunaev A. V. Multimodal optical diagnostics of microcirculatory tissue systems of the human body, 440 (Monograph, Stary Oskol, 2022).</mixed-citation>
     <mixed-citation xml:lang="en">Dunaev A. V. Multimodal optical diagnostics of microcirculatory tissue systems of the human body, 440 (Monograph, Stary Oskol, 2022).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B23">
    <label>23.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Sidorov V. V., Rybakov Yu. L., Gukasov V. M., Yevtushenko G. S. System of local analyzers for non-invasive diagnostics of the general condition of the compartments of the microcirculatory tissue system of human</mixed-citation>
     <mixed-citation xml:lang="en">Sidorov V. V., Rybakov Yu. L., Gukasov V. M., Yevtushenko G. S. System of local analyzers for non-invasive diagnostics of the general condition of the compartments of the microcirculatory tissue system of human</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B24">
    <label>24.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Rodichkin P. V., Regulation of motor functions in high-class athletes and its optimization with the help of adaptogens, antihypoxants and hyperbaric oxygenation, Dis. ... doc. honey. Sciences, 321 (St. Petersburg,</mixed-citation>
     <mixed-citation xml:lang="en">Rodichkin P. V., Regulation of motor functions in high-class athletes and its optimization with the help of adaptogens, antihypoxants and hyperbaric oxygenation, Dis. ... doc. honey. Sciences, 321 (St. Petersburg,</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B25">
    <label>25.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Vogel H. G. Drug discovery and evaluation pharmacological assays, 2129 (Springer, 2008).</mixed-citation>
     <mixed-citation xml:lang="en">Vogel H. G. Drug discovery and evaluation pharmacological assays, 2129 (Springer, 2008).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B26">
    <label>26.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Burmistrova  L. A., Physico-chemical analysis and biochemical assessment of the biological activity of drone brood: abstract. diss. Candidate of Biology Sciences, 22 (Ryazan, 1999).</mixed-citation>
     <mixed-citation xml:lang="en">Burmistrova  L. A., Physico-chemical analysis and biochemical assessment of the biological activity of drone brood: abstract. diss. Candidate of Biology Sciences, 22 (Ryazan, 1999).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B27">
    <label>27.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Kozlov V. I., Sakharov V. N., Gurova O. A., Sidorov V. V., Assessment of the state of microcirculation in  children  6–7  years  old  according  to  laser  Doppler  flowmetry,  Regional  blood  circulation  and</mixed-citation>
     <mixed-citation xml:lang="en">Kozlov V. I., Sakharov V. N., Gurova O. A., Sidorov V. V., Assessment of the state of microcirculation in  children  6–7  years  old  according  to  laser  Doppler  flowmetry,  Regional  blood  circulation  and</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B28">
    <label>28.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Stefanovska  A.,  Bracic  M.,  Kvernmo  N.  D.,  Wavelet  analysis  of  oscillations  in  the  peripheral  blood circulation measured by laser Doppler technique, Trans Biomed Eng., 46, 10, 1230 (1999).</mixed-citation>
     <mixed-citation xml:lang="en">Stefanovska  A.,  Bracic  M.,  Kvernmo  N.  D.,  Wavelet  analysis  of  oscillations  in  the  peripheral  blood circulation measured by laser Doppler technique, Trans Biomed Eng., 46, 10, 1230 (1999).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B29">
    <label>29.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Bartolom F., Abramov A. Y., Measurement of mitochondrial NADH and FAD autofluorescence in live cells, Mitochondrial Medicine, 263 (2015).</mixed-citation>
     <mixed-citation xml:lang="en">Bartolom F., Abramov A. Y., Measurement of mitochondrial NADH and FAD autofluorescence in live cells, Mitochondrial Medicine, 263 (2015).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B30">
    <label>30.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Krupatkin A. I., Sidorov V. V., Functional diagnostics of the state of microcirculatory tissue systems: Oscillations, information, nonlinearity, Guide for doctors. Ed. 2nd., 496 (LENNAND, Moscow, 2016).</mixed-citation>
     <mixed-citation xml:lang="en">Krupatkin A. I., Sidorov V. V., Functional diagnostics of the state of microcirculatory tissue systems: Oscillations, information, nonlinearity, Guide for doctors. Ed. 2nd., 496 (LENNAND, Moscow, 2016).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B31">
    <label>31.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Heikal  A.  Intracellular  coenzymes  as  natural  biomarkers  for  metabolic  activities  and  mitochondrial anomalies, Biomarkers in Medicine, 4, 2, 241 (2010).</mixed-citation>
     <mixed-citation xml:lang="en">Heikal  A.  Intracellular  coenzymes  as  natural  biomarkers  for  metabolic  activities  and  mitochondrial anomalies, Biomarkers in Medicine, 4, 2, 241 (2010).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B32">
    <label>32.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Luo X., Li R., Yan L.-Jun., Roles of Pyruvate, NADH, and Mitochondrial Complex 1 in Redox Balance and Imbalance in Cell Function and Dysfunction, Diabetes Res., 1 (2015).</mixed-citation>
     <mixed-citation xml:lang="en">Luo X., Li R., Yan L.-Jun., Roles of Pyruvate, NADH, and Mitochondrial Complex 1 in Redox Balance and Imbalance in Cell Function and Dysfunction, Diabetes Res., 1 (2015).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B33">
    <label>33.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Karnaukhov V. N. Luminescent analysis of cells, 131 (2002).</mixed-citation>
     <mixed-citation xml:lang="en">Karnaukhov V. N. Luminescent analysis of cells, 131 (2002).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B34">
    <label>34.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Glagoleva E. N., Sidorov V. V., Podoplekina N. D., Fayzullina D. R. Assessment of  microcirculatory tissue  systems  after  cosmetic  procedures  aimed  at  correcting  age-related  changes,  Regional  blood</mixed-citation>
     <mixed-citation xml:lang="en">Glagoleva E. N., Sidorov V. V., Podoplekina N. D., Fayzullina D. R. Assessment of  microcirculatory tissue  systems  after  cosmetic  procedures  aimed  at  correcting  age-related  changes,  Regional  blood</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B35">
    <label>35.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Samoilov  V.  O.  Fluorescence  of  components  of  the  mitochondrial  respiratory  chain  in  medical diagnostics, Biophysics, 58, 5, 813 (2013).</mixed-citation>
     <mixed-citation xml:lang="en">Samoilov  V.  O.  Fluorescence  of  components  of  the  mitochondrial  respiratory  chain  in  medical diagnostics, Biophysics, 58, 5, 813 (2013).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B36">
    <label>36.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Shabrykina N. S. Biomechanical model of microcirculation and transcapillary metabolism., Diss... cand. fm. Sci., 159 (Saratov, 2008).</mixed-citation>
     <mixed-citation xml:lang="en">Shabrykina N. S. Biomechanical model of microcirculation and transcapillary metabolism., Diss... cand. fm. Sci., 159 (Saratov, 2008).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B37">
    <label>37.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Vlasov T. D., Kornyushin O. V., Papayan G. V. Possibilities of autofluorescent organoscopy for ischemic and reperfusion injury of the small intestine in vitro, Regional blood circulation and microcirculation, 2,</mixed-citation>
     <mixed-citation xml:lang="en">Vlasov T. D., Kornyushin O. V., Papayan G. V. Possibilities of autofluorescent organoscopy for ischemic and reperfusion injury of the small intestine in vitro, Regional blood circulation and microcirculation, 2,</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B38">
    <label>38.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Kvernmo  H.  D.,  Stefanovska  A.,  Kirkeboen  K.  A.,  Kvernebo  K.  Oscillations  in the  human  cutaneous blood  perfusion  signal  modified  by  endothelium-dependent  and  endothelium-independent</mixed-citation>
     <mixed-citation xml:lang="en">Kvernmo  H.  D.,  Stefanovska  A.,  Kirkeboen  K.  A.,  Kvernebo  K.  Oscillations  in the  human  cutaneous blood  perfusion  signal  modified  by  endothelium-dependent  and  endothelium-independent</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B39">
    <label>39.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Dunaev A. V. Method for assessing adaptive changes in microcirculatory tissue systems of the human body, Fundamental and applied problems of engineering and technology, 4, 1, 88 (2020).</mixed-citation>
     <mixed-citation xml:lang="en">Dunaev A. V. Method for assessing adaptive changes in microcirculatory tissue systems of the human body, Fundamental and applied problems of engineering and technology, 4, 1, 88 (2020).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B40">
    <label>40.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Katayama  K.,  Matsuo  H.,  Ishida  K.  et  al.,  Intermittent  hypoxia  improves  endurance  performance  and submaximal efficiency exercise, High. Alt. Med. Biol., 4, 3, 291 (2003).</mixed-citation>
     <mixed-citation xml:lang="en">Katayama  K.,  Matsuo  H.,  Ishida  K.  et  al.,  Intermittent  hypoxia  improves  endurance  performance  and submaximal efficiency exercise, High. Alt. Med. Biol., 4, 3, 291 (2003).</mixed-citation>
    </citation-alternatives>
   </ref>
   <ref id="B41">
    <label>41.</label>
    <citation-alternatives>
     <mixed-citation xml:lang="ru">Millet G. P., Roels B., Schmitt L. et al., Combining hypoxic methods for peak performance, Sports Med, 40, 1 (2010).</mixed-citation>
     <mixed-citation xml:lang="en">Millet G. P., Roels B., Schmitt L. et al., Combining hypoxic methods for peak performance, Sports Med, 40, 1 (2010).</mixed-citation>
    </citation-alternatives>
   </ref>
  </ref-list>
 </back>
</article>
