Russian Federation
Currently, the issues of diagnosis of hypoxic-ischemic encephalopathy (cerebral ischemia) in premature newborns are relevant all over the world. The frequency of occurrence of hypoxic-ischemic encephalopathy is from 2 to 9 cases per 1000 newborns, there are negative consequences: 10–15% – fatal, 25–30% disability. The purpose of the study is to determine the clinical and neurological features of cerebral ischemia of varying severity in premature newborns using the Sarnat scale. As a result of the survey of premature newborns with cerebral ischemia, new data on the clinical and neurological status of premature children were obtained on the Sarnat classification, which can be widely used for further diagnostics and when choosing therapeutic tactics.
premature newborns, Sarnat classification, cerebral ischemia, neonatal electroencephalograph
1. Chalak L. F. Perinatal acidosis and hypoxic-ischemic encephalopathy in preterm infants of 33 to 35 weeks’ gestation. J. Pediatr. 2012; 160:388-394. doi:https://doi.org/10.1016/j.jpeds.2011.09.001.
2. Volpe J. J. Neurology of the newborn. 5nd ed. Philadelphia; 2008.
3. Gopagondanahalli K. R. Preterm hypoxic-ischemic encephalopathy.Pediatrics. 2016;4:114. doi:https://doi.org/10.3389/fped.2016.00114
4. Herrera T. I. Outcomes of preterm infants treated with hypothermia for hypoxic-ischemic encephalopathy. Early Hum. Dev. 2018; 125: 1-7. doi:https://doi.org/10.1016/j.earlhumdev.2018.08.003.
5. Sarnat H. B., Sarnat M. S. Neonatal encephalopathy following fetal distress. A clinical and electroencephalographic study. Arch. Neurol. 1976;33:696-705. doi.org/10.1001/archneur.1976.00500100030012
6. Shankaran S. Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N. Engl. J. Med. 2015;353:1574-1584. doi:https://doi.org/10.1056/NEJMcps050929.
7. Pal'chik A. B. Lekcii po nevrologii razvitiya. M: «MEDpress-inform»;2017:368
8. Zhurba L. T., Mastyukova E. A. Narushenie psihomotornogo razvitiya detey pervogo goda zhizni. M.: Medicina;1990:276-300.
9. Volodin N. N. Aktual'nye problemy perinatal'noy nevrologii na sovremennom etape Zhurnal nevrologii i psihiatrii im. S.S. Korsakova. 2017;7:4 - 9.
10. Pal'chik A. B., Shabalov N. P. Gipoksicheski-ishemicheskaya encefalopatiya novorozhdennyh. M.: MEDPRESS-Inform, 2020.
11. Chalak L. F., Rouse, D. J. Neuroprotective approaches: before and aƌer delivery. Clin. Perinatol. 2016;38:455-470. .doi.org/10.1016/j.clp.2011.06.012.
12. Romeo D. M. Neonatal neurological examination of late preterm babies. Early Hum. Dev. 2013;89:537-545. doi:https://doi.org/10.1016/j.earlhumdev.2013.01.002.
13. Maitre N. L., Chorna O., Romeo D. M., Guzzeta A. Implementation of the Hammersmith Infant Neurological Exam in a high-risk infant follow-up program. Pediatr. Neurol. 2016;65: 31-38. doi:https://doi.org/10.1016/j.pediatrneurol.2016.09.010.
14. Gunn A. J., Bennet L. Brain cooling for preterm infants. Clin. Perinatol. 2018;35:735-748. doi:https://doi.org/10.1016/j.clp.2008.07.012.
15. Rao R. Safety and short-term outcomes of therapeutic hypothermia in preterm neonates 34-35 weeks gestational age with hypoxic-ischemic encephalopathy. J. Pediatr. 2017;183:37-42. doi:https://doi.org/10.1016/j.jpeds.2016.11.019
