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Tavricheskiy Mediko-Biologicheskiy Vestnik
Journals / Tavricheskiy Mediko-Biologicheskiy Vestnik / Volume 28 Issue 1 / THE DIFFICULTY OF DIAGNOSIS OF OBSTRUCTIVE JAUNDICE IN A MULTIDISCIPLINARY HOSPITAL (CLINICAL CASE)
UDC 61

THE DIFFICULTY OF DIAGNOSIS OF OBSTRUCTIVE JAUNDICE IN A MULTIDISCIPLINARY HOSPITAL (CLINICAL CASE)

Published in Tavricheskiy Mediko-Biologicheskiy Vestnik · Volume 28, Issue 1 · Pages 57–61 · Rubric: Clinical observations
DOI: https://doi.org/10.29039/2070-8092-2025-28-1-57-61
Received: 01.12.2025 Accepted: 03.12.2025 Published: 03.12.2025
Authors
SV
Svetlana Styazhkina
A.
A. A. Yakovlev
R.
R. K. Ayubov
SH
Sh. U. Tahirov
ABSTRACT
Klatskin tumor is a rare and aggressive malignant neoplasm that is difficult to diagnose in its early stages due to overlapping symptoms with other biliary tract diseases. Modern imaging methods, including ultrasound, CT, and MRI, significantly improve diagnostic accuracy. However, diagnostic delays are still observed in clinical practice, which often leads to serious complications such as acute biliary pancreatitis, cholangitis, sepsis, and multiple organ failure. Delays in diagnosis or initiation of treatment worsen the prognosis for patients, underscoring the need for improved approaches to early diagnosis, comprehensive examination, and better treatment strategies. To assess the challenges of diagnosing and treating Klatskin tumor in a multidisciplinary hospital setting based on clinical cases of patients with obstructive jaundice. Two clinical cases of patients with Klatskin tumor are presented. Diagnostic challenges and treatment strategies at various stages of the disease are described. Results. In all cases, patients presented with symptoms of obstructive jaundice, which complicated early diagnosis. Delays in accurate diagnosis led to disease progression and complications, including pancreonecrosis and multiple organ failure. Surgical tactics included percutaneous biliary drainage, but radical operations were hindered by the advanced stage of the tumor. The treatment was primarily palliative. Early diagnosis and timely surgical correction of bile duct obstruction significantly improve the prognosis for patients with Klatskin tumor. Diagnostic errors and treatment delays increase the risk of complications and mortality, highlighting the need for strict adherence to clinical guidelines.
KEYWORDS
Klatskin tumor, obstructive jaundice, diagnosis, multidisciplinary hospital, differential diagnosis, etiology.
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