Rossiyskiy nauchnyy centr hirurgii im. akad B. V. Petrovskogo
Oblastnaya detskaya klinicheskaya bol'nica
Purulent pathology accounts for more than 70% of the structure of surgical diseases, while purulent inflammatory processes of soft tissues make up a significant proportion of it, and the most often recommended treatment method is antibacterial therapy. However, currently the primary care physician is faced with the task of f inding ways to treat with minimal use of antibiotics due to the development of antibiotic-resistant strains and a significant number of complications. The article presents the results of treatment of a 15-year-old patient with an extensive bruised ankle and foot wound. Patient was successfully treated with topical application of an alcohol solution of 0.027% chlorhexidine bigluconate without the use of systemic antibacterial drugs. The patient was treated with the removal of old gauze bandages, rinsing with a 3% solution of hydrogen peroxide, then the wound was closed with a gauze cloth moistened with 0.027% alcohol solution of chlorhexidine bigluconate, as well as a f ixing gauze bandage. The procedure was repeated 6-8 times during the day. The percentage of components of the solution used was: chlorhexidine 0.05% – 50%, rectified ethyl alcohol 95% – 21.1%, distilled water – 28.9%. The patient managed to stop the inflammatory process of the soft tissues of the ankle joint and foot with the use of a weakly concentrated alcoholic solution of chlorhexidine bigluconate, as well as to abandon the use of systemic antibacterial drugs. At the same time, there was no chemical burn and tanning of the skin and soft tissues of the wound area, the procedure was easily tolerated by the patient, did not cause painful sensations, and therefore can be recommended for use.
contused wounds, chlorhexidine bigluconate solution, antibacterial therapy, antibiotic resistance, inflammation, Pseudomonas aeruginosa
1. Mokhov E. M., Armasov G. A., Amrulaeva G. A. Evaluation of the effectiveness of topical application of perfluorane in the treatment of suppurative processes of soft tissues. Bulletin of Experimental and Clinical Surgery
2. Pediatric surgery: a scientific guide. Y. F. sakov, eds. M.; 2009. (In Russ.).
3. Khairutdinova A. G., Kulagina L. Yu., Valiullina I. R. Clinical pharmacology of antibacterial drugs in pediatrics. Practical Medicine 2021;19(4):2631. (In Russ.). doihttps://doi.org/10.32000/2072-1757-2021-4-2631.
4. Orlova N. V. Antibiotic resistance and modern strategy of antibacterial therapy. Meditsinskiy sovet = Medical Council. 2022; (8):89-97. (In Russ.). doihttps://doi.org/10.21518/2079-701X-2022-16-8-89-97.
5. Ilyina S. V. Irrational use of antibiotics in medicine: the crisis of antibiotic resistance, and what we can do. Pediatric pharmacology. 2017; 14 (6): 508–514. (In Russ.). doihttps://doi.org/10.15690/pf.v14i6.1834.
6. Kalugina D. Yu., Kuznetsova Yu. E., Redozubova E. V., et al Antibiotics. Side effects and complications of antibiotic therapy. Principles of rational antibiotic therapy. International Student Scientific Bulletin 2014;(4):41. (In Russ.).
7. Chernenkaya T. V. Pseudomembranous colitis: diagnosis, treatment and prevention (literature review). N. V. Sklifosovsky Journal Emergency Medical Care 2016;(1):33-39. (In Russ.).
8. Shlyapnikov S. A., Naser N. R., Batyrshin I. M., et al Antibiotic-associated colitis is a new problem in surgery. Bulletin of the National Medical and Surgical Center named after N.I. Pirogov. 2020;15(2):138-142. (In Russ.)
9. Surkov A. N. Possibilities of probiotic therapy in the complex treatment of antibioticassociated diarrhea in children. Issues of modern Pediatrics 2011; 10 (2):132-136. (In Russ.).
10. Global action plan on antimicrobial resistance, WHO. URL: http://apps.who.int/iris/bitstr eam/10665/193736/1/9789241509763_eng.pdf?ua=1 (Accessed December 14, 2024). (In Russ.).
11. Denton G. W. Chlorhexidine. In: Block S., ed. Disinfection, Sterilization, and Prevention. Philadelphia. 2000;321-36.
12. Patent RU № 2818152 C1. Publ. 24.04.2024, Byul. No. 12. Sarkisyan O. G., Parkhomin I. A., Parkhomina N. A., Cherepanova A. A., Tsupka A. S., Loseva T. D., Surkov A. N. Method of treatment of purulent-inflammatory



