СОВРЕМЕННЫЕ ПРЕДСТАВЛЕНИЯ ОБ ИММУНОИНДУЦИРОВАННОМ ПРОЦЕССЕ В МЫШЦАХ ПРИ ФИЗИЧЕСКИХ НАГРУЗКАХ
Аннотация и ключевые слова
Аннотация (русский):
Регулярная физическая нагрузка оказывает положительное влияние на организм и мышцы в целом, позволяя повысить выносливость, силу, а также предупредить развитие целого ряда заболеваний. Однако действие длительных нагрузок может спровоцировать развитие воспалительных реакций, которые способны вызвать снижение эффективности работы мышечного волокна. Согласно классическим представлениям, ключевыми маркерами воспаления как в организме, так и в мышцах являются цитокины. Однако современные данные доказывают, что цитокины не являются лимитирующим фактором развития воспаления, а входят в состав сложных функциональных систем, так как способны продуцироваться не только при физической нагрузке. В рамках данной публикации нами проведен теоретический анализ возможного механизма развития воспалительной реакции в мышцах с целью выявления ключевых элементов данного процесса.

Ключевые слова:
мышцы, иммунологическая реакция, оксид азота, цитокины, воспаление, вагус, кальпаин.
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